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KMID : 1101320130450010009
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Korean Journal of Clinical Laboratory Science
2013 Volume.45 No. 1 p.9 ~ p.15
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Correlation of Chronic Hepatitis B Virus Infection with Diabetes Mellitus Indicators
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Lee Jung-Hwa
Hyun Sung-Hee
Park Kap-Tae
Ahn Tae-Ho
Kim In-Sik
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Abstract
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Hepatitis B virus (HBV) infection has recently shown to be associated with diabetes mellitus. The objective of this study was to investigate the relationship between chronic hepatitis B and diabetes mellitus indicators. We evaluated anthropometry, metabolic syndrome risk factors, fasting glucose, HbA1c, and C-peptide among the normal and HBV subjects. The partial correlation and average comparison analysis were used to assess the independent association between chronic hepatitis B and diabetes mellitus indicators. Average comparisons of normal and HBV subjects were significantly different in fasting glucose (p＜0.000), HbA1c (p＜0.000), C-peptide (p＜0.000), alanine transaminase (ALT) (p＜0.000) and aspartate transaminase (AST) (p＜0.000). We may suggest that HBV infection is related to diabetes mellitus indicators such as fasting glucose, HbA1c and C-peptide.
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KEYWORD
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Chronic hepatitis B, Diabetes mellitus, Fasting glucose, HbA1c, C-peptide
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